What does xanthine oxidase do
Xanthine oxidase (xo) is an enzyme found in many species, including humans, and primarily functions in the catabolism of purine nucleic acids.Become an examine member to get access to the latest research.For example, zikakis and wooters (1980) reported an average xanthine oxidase activity (38 °c and ph 7.5) of 61.2 μl/o 2 (40 u/l), while cerbulis and farrell (1976) reported xanthine oxidase.Xanthine oxidase is a form of xanthine oxidoreductase, an enzyme that generates reactive oxygen species such as superoxide radicals and hydrogen peroxide when it catalyzes the oxidation of hypoxanthine to xanthine, and can further catalyze the oxidation of xanthine to uric acid.What does xanthine oxidase do in the body?
Xanthine oxidase inhibitors are medications prescribed for the treatment of gout, a painful condition caused by excessive uric acid levels in the blood (hyperuricemia).Excessive production and/or inadequate excretion of uric acid results in hyperuricemia.These enzymes catalyze the oxidation of hypoxanthine to xanthine and can further catalyze the oxidation of xanthine to uric acid.these enzymes play an important role in the catabolism of purines in some species, including humans.What kind of drug is theophylline?The role of xanthine oxidase in thiopurine metabolism:
Excessive production and/or inadequate excretion of uric acid results in hyperuricemia.Azathioprine (aza) is widely used in the treatment of autoimmune inflammatory diseases.